A new method called ReadsRatio estimates tissue contributions to circulating cell-free DNA from unmethylated read ratios in ...

Like people, bacteria have their preferences when it comes to relationships. Some are totally independent, while others prefer company. Salmonella and many other kinds of bacteria are of the social ...

Studying T cells, the immune cells most responsible for responding to infections and cancers, just received a significant boost in the form of a new technique from St. Jude Children's Research ...

When reading articles about genetic testing, terms like PCR, Sanger sequencing, NGS, and digital PCR often appear.While all of these are technologies used to examine DNA and genes, how do they differ?

A targeted deep sequencing method simultaneously estimates mosaic Y chromosome loss and CHIP-related mutations, validated in ...

An easily implemented genome-sequencing method could help public health officials combat America's ongoing syphilis epidemic, researchers at the University of Washington School of Medicine and Public ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

A new spatial transcriptomics method maps gene expression in archived FFPE tissue at single-cell resolution, expanding ...

Long-read sequencing studies found genetic alterations missed by conventional sequencing and traced the origin of a rare pediatric tumor after gene therapy ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...