An experimental treatment for HD developed by Alnylam has shown long-lasting huntingtin lowering after just one dose, with ...

A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin ...

The lines between HD and catatonia may sometimes be blurred. However, recognising that occasionally there can be more than ...

For decades, Huntington’s disease (HD) research has focused on what goes wrong inside vulnerable brain cells. But neuronsneuron Brain cells that store and transmit information don’t work alone, they ...

This Fall, HDBuzz is proud to launch our “Falling Into Hope” fundraising campaign. Our goal is simple but ambitious: raise $30,000 in the next 8 weeks, by October 28. 2025 will be a landmark year in ...

In plain language. Written by scientists. A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin interferes with chemical marks on DNA ...

A recent collaboration between researchers at the University of Leiden and the Huntington Expertise Center Topaz Overduin in the Netherlands has focused on an important yet often overlooked part of ...

Skyhawk Therapeuticstherapeutics treatments announced on March 3, 2026 that Australia’s Therapeutic Goods Administration (TGA) has determined that SKY-0515, an small molecule drug that can be taken as ...

Day 1 of HD2026 is a wrap! From what human brains can teach us about HD, to HTT1a, somatic CAG expansion and the normal biology of HTT, today’s talks spanned the spectrum from fundamental biology to ...

This week, we heard an update from Roche about their huntingtin-lowering therapy, tominersen, currently being tested in the GENERATION HD2 trial. An independent data monitoring committeemonitoring ...

Day 3 of #HD2026 put HTT under the microscope. Researchers shared new insights into HTT1a, next-generation HTT-lowering approaches, somatic expansion, brain circuitry, and why boosting healthy HTT ...

A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, uncovering how runaway CAG repeats erode cell identity in certain types of ...