A newly mapped step in DNA replication suggests that strand separation begins at a precise junction between two helicase rings. Credit: Shutterstock Researchers mapped where DNA first opens and how a ...

In a study that appears in the journal Cell, scientists from San Francisco-based Gladstone Institutes—including co-first author Megan Ostrowski (left) and senior author Vijay Ramani, PhD ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, ...