Most people are familiar with the DNA double-helix. Its twisted ladder shape forms because the long pieces of DNA that make up our genome are exactly complementary—every adenine paired to a thymine, ...
A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA origami for silicon surfaces and investigated how different conditions affect ...
Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.
The name is an analogy: no paper is folded. Specially chosen staple sequences bring distant parts of the scaffold together to form flat patterns, three-dimensional blocks or open wireframe structures, ...
One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...
A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.
DNA origami cages constrain individual proteins toward preferred orientations on electrodes, dramatically improving electrical measurement precision and enabling detection of subtle structural changes ...
Previously, vaccinologists decorated therapeutic nanoparticles with CpG adjuvants. 6 However, William Shih, a synthetic biologist at Harvard University and an author of the Nature Nanotechnology paper ...
DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...