Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...
A new computational framework, Akita Semifreddo, combines a fast genome folding model with sequence optimization to design ...
Imagine if you could "print" a tiny skyscraper using DNA instead of steel. That’s what researchers at Columbia and Brookhaven are doing—constructing intricate 3D nanostructures by harnessing the ...